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Journal of Pharmacology And Experimental Therapeutics, Vol. 49, Issue 3, 270-282, 1933
Copyright © 1933 by American Society for Pharmacology and Experimental Therapeutics

STUDIES IN CANCER CHEMOTHERAPY XI. THE EFFECT OF CO, HCN, AND PITUITRIN UPON TUMOR GROWTH

L. C. MAXWELL 1, FRITZ BISCHOFF 1, and HENRY ULLMANN JR. 1

1 From the Department of Cancer Research, Santa Barbara Cottage Hospital, Santa Barbara, California

Exposure of animals bearing transplantable tumors to carbon monoxide and to hydrogen cyanide resulted in a decrease in the rate of tumor growth.

Sublethal dosage with pituitrin did not influence the rate of tumor growth.

Lipoid and cholesterol values for the tumors, and lipoid and glycogen values for the body tissues, of mice exposed to atmospheres containing CO or HCN, or dosed with pituitrin, showed no significant variation from the controls.

Submitted on January 30, 1933






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