JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by COTUI, F. W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by COTUI, F. W.
Journal of Pharmacology And Experimental Therapeutics, Vol. 48, Issue 2, 223-228, 1933
Copyright © 1933 by American Society for Pharmacology and Experimental Therapeutics

THE INTRACISTERNAL MINIMUM LETHAL DOSE OF PROCAINE HYDROCHLORIDE (NOVOCAIN) IN DOGS

FRANK WANG COTUI 1

1 From the Department of Surgical Research, New York University and Bellevue Medical College, New York City

1. The minimal lethal dose of procaine hydrochloride; that is, the dose which causes paralysis of the respiratory center, when injected into the cisterna magna of dogs, bears a closer relationship to the spinal length than to the weight of the dog.

2. In the sample of procaine hydrochloride thus tested (Metz) the m.l.d. lay between 1.3 and 1.5 mgm. per centimeter spinal length.1

Submitted on October 17, 1932






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1933 by the American Society for Pharmacology and Experimental Therapeutics.