JPET Introducing ALZET?ew Model 2006 Pump

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Journal of Pharmacology And Experimental Therapeutics, Vol. 48, Issue 2, 175-181, 1933
Copyright © 1933 by American Society for Pharmacology and Experimental Therapeutics

SOME NEW ALKAMINES IN THE TETRAHYDRONAPHTHALENE SERIES

GERALD G. WOODS 1 and NATHAN B. EDDY 1

1 From the Laboratory of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan

The toxic picture in mice and rabbits and some other effects in rabbits and cats of three new alkamines of the naphthalene series have been described.

These substances bear considerable resemblance to procain. They are emetic but not analgesic for cats; they stimulate respiration and oxygen consumption to some extent in rabbits, and they exhibit local anesthetic action. The anesthetic efficiency of each of them is definitely less than that of procain.

Submitted on September 21, 1932






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Copyright © 1933 by the American Society for Pharmacology and Experimental Therapeutics.