ETHERS AND THIO-ETHERS OF TRIETHYLAMMONIUM COMPOUNDS

¹ From the Pharmacological Laboratory of the Harvard Medical School and the Laboratory of Organic Chemistry, New York University

None of the triethyl-ammonium compounds have a "muscarine" or "stimulating nicotine action." They have a "paralyzing nicotine" action; the allyloxymethyl and the n-butoxyethyl-ethers were the most active of the aliphatic series but the phenoxyethyl ether was somewhat more active.

The thiomethyl ethers were perhaps somewhat more active in this respect than the oxygen ethers; of these investigated the iso-butyl ether was the most active. It had a powerful but brief curare action.