JPET Celsis microsomes equal better data

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by JONES, H. D.
Right arrow Articles by HENRY, C. R.
Right arrow Search for Related Content
PubMed
Right arrow Articles by JONES, H. D.
Right arrow Articles by HENRY, C. R.
Journal of Pharmacology And Experimental Therapeutics, Vol. 48, Issue 1, 1-23, 1933
Copyright © 1933 by American Society for Pharmacology and Experimental Therapeutics

A STUDY OF THE EFFECTS OF AGAVE CONCENTRATE IN THE TREATMENT OF EXPERIMENTAL NEPHRITIS INDUCED IN ANIMALS I. NEPHRITIS INDUCED IN RABBITS BY THE USE OF TARTRATES

HERMAN D. JONES 1, KEITH D. CRANE 1, G. BERNARD JOHNSTON 1, and C. R. HENRY 1

1 From the Laboratory of Biological Chemistry, Department of Chemistry, Alabama Polytechnic Institute, Auburn, Alabama

Briefly, the significant observations may be summarized as follows:

1. Uniformly fatal nephritis was produced in control rabbits by the injection of standardized doses of tartrate (3,4).

2. Forty-three of 59 animals receiving a fatal dose of tartrate recovered when given the concentrate by mouth.

3. Twenty-nine of the 33 control animals receiving the tartrate and no agave concentrate died.

4. With the animals receiving the concentrate, the blood chemistry showed a marked and definite improvement, as compared with the control animals, and also with the results reported by Underhill and Wakeman (3,4).

5. Microscopic examination of the kidney showed a definitely better pathological picture in animals receiving the concentrate, as compared with the controls.

Submitted on July 23, 1932






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1933 by the American Society for Pharmacology and Experimental Therapeutics.