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1 From the Department of Pharmacology, The University of Manchester
The effects of the introduction of local anesthetics into the cerebrospinal fluid of the cat are described and discussed in relation to the problems of spinal anesthesia. it is shown that the incidence of a dangerously toxic action is always, in the long run, on the respiratory system, although circulatory depression may contribute. In the cat adequate and timely artificial respiration serves as a reliable antidote to novocain poisoning.
Submitted on June 22, 1932