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Journal of Pharmacology And Experimental Therapeutics, Vol. 45, Issue 4, 419-426, 1932
Copyright © 1932 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECT OF CALCIUM ON THE RESPONSE OF ISOLATED BRONCHI TO HISTAMINE

MARJORIE GILLESPIE 1 and J. W. THORNTON 1

1 From the Department of Physiology, King's College, London

1. It has been shown that the isolated bronchial muscle of guinea pigs is sensitive to changes as low as 1 mgm. per cent in ionic concentration of calcium as measured by the response to histamine.

2. A seasonal variation in the response to histamine in guinea pigs has been noted.

3. The significance of these factors is discussed.

Submitted on December 24, 1931






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