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Journal of Pharmacology And Experimental Therapeutics, Vol. 42, Issue 2, 233-244, 1931
Copyright © 1931 by American Society for Pharmacology and Experimental Therapeutics

THE INFLUENCE OF ADRENALIN, PITUITRIN, HISTAMINE AND PEPTONES ON THE VOLUME OF THE LIVER

FREDERICK E. EMERY 1 and FRED R. GRIFFITH JR. 1

1 From the Department of Physiology, University of Buffalo, Buffalo, New York

1. Adrenalin and pituitrin constrict the liver simultaneously with the rise in blood pressure when injected into the hepatic artery, portal or femoral vein.

2. Adrenalin dilates the liver during: (a) depressor responses in blood pressure, and (b) sometimes when pressor doses are given if the cat is in poor condition.

3. Histamine and peptone cause a diminution in liver volume which in case of histamine is probably an active contraction of the liver vessels.

4. An atypical response to histamine resulting in an increase in liver volume is discussed.

Submitted on January 30, 1931






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Copyright © 1931 by the American Society for Pharmacology and Experimental Therapeutics.