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Journal of Pharmacology And Experimental Therapeutics, Vol. 42, Issue 1, 99-105, 1931
Copyright © 1931 by American Society for Pharmacology and Experimental Therapeutics

LACTIC ACID FORMATION IN CONTRACTURES

ALBERT H. HEGNAUER 1

1 From the Department of Physiology, The University of Rochester School of Medicine and Dentistry, Rochester, New York

1. An increased lactic acid concentration is demonstrated in certain frog muscles in contractures induced by acetylcholine.

2. Contractures caused by HCl are accompanied by an increased lactic acid content.

3. After treatment with iodo-acetic acid, muscles placed in caffeine or KCl will exhibit tensions and increased 02 consumption equal to normal muscles, but without an increase in lactic concentration.

Submitted on December 15, 1930






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Copyright © 1931 by the American Society for Pharmacology and Experimental Therapeutics.