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Journal of Pharmacology And Experimental Therapeutics, Vol. 42, Issue 1, 35-43, 1931
Copyright © 1931 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECT OF BENZYL ESTERS ON THE INTACT INTESTINE OF NON-ANESTHETIZED DOGS

C. M. GRUBER 1, C. S. DRAYER 1, W. M. CRAWFORD 1, and W. W. GREENE 1

1 From the Department of Pharmacology, Washington University, School of Medicine, Saint Louis, Missouri

1. Benzyl-esters do not affect the intact intestine in non-anesthetized dog in the same manner as they do excised rabbit intestine exposed to the drug.

2. In our experiments benzyl-acetate injected intravenously caused an increase in the rate and vigor of the peristaltic contractions, as a rule, though one animal showed a decrease in general tonus.

Submitted on December 5, 1930






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