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Journal of Pharmacology And Experimental Therapeutics, Vol. 40, Issue 3, 341-350, 1930
Copyright © 1930 by American Society for Pharmacology and Experimental Therapeutics

THRESHOLD RELATIONSHIPS OF TESTIS HORMONE INDICATORS IN MAMMALS; THE RAT UNIT

CARL R. MOORE 1 and T. F. GALLAGHER 1

1 Departments of Zoology and of Physiological Chemistry, The University of Chicago

In point of sensitivity the mammalian testis hormone indicators rank in the order (a) spermatozoon motility test, (b) prostate cytology test, (c) seminal vesicle, Cowper's gland, and vas deferens tests, (d) electric ejaculation test.

The rat unit of male hormone is defined in terms of dosages that effect complete replacement of the internal secretion of the testis.

Approximately one-twentieth of a rat unit is detectable by the prostate gland and one-sixth of a unit by the seminal vesicles, Cowper's gland and vas deferens.

One rat unit is approximately the equivalent of six bird units, as defined by Gallagher and Koch.

Submitted on July 30, 1930






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