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Journal of Pharmacology And Experimental Therapeutics, Vol. 40, Issue 2, 207-214, 1930
Copyright © 1930 by American Society for Pharmacology and Experimental Therapeutics

RESISTANCE TO MORPHINE IN EXPERIMENTAL UREMIA

EATON M. MACKAY 1 and LOIS LOCKARD MACKAY 1

1 From the Department of Medicine of Stanford University Medical School, San Francisco

The tolerance to morphine intoxication whether produced by morphine given hypodermically, intraperitoneally, intravenously or by stomach tube is increased by the production of the experimental uremia which follows double nephrectomy in the albino rat. The mechanism of this increased resistance to morphine is unknown.

Submitted on July 7, 1930






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Copyright © 1930 by the American Society for Pharmacology and Experimental Therapeutics.