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Journal of Pharmacology And Experimental Therapeutics, Vol. 30, Issue 2, 185-191, 1926
Copyright © 1926 by American Society for Pharmacology and Experimental Therapeutics

THE CHOLERETIC ACTION OF TOLYSIN (ETHYL ESTER OF PARA METHYL PHENYLCINCHONIC ACID) IN CHOLECYSTOGRAPHY A PRELIMINARY REPORT

R. G. SPURLING 1 and E. E. HARTMAN 1

1 From the Surgical Service and the Laboratory for Experimental Surgery University of Louisville, School of Medicine, Louisville, Kentucky

1. The time for the production of cholecystographic shadows, and for their attainment of maximum density, can apparently be shortened approximately one-half by the administration of 1 gram of tolysin by mouth prior to the intravenous administration of the usual dose of sodium tetra-iodo-phenolphthalein.

2. The expectation from its choleretic action, that tolysin would increase the speed of excretion of the halogenated phenolphthaleins by the liver, is thus far confirmed.

Submitted on October 22, 1926






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Copyright © 1926 by the American Society for Pharmacology and Experimental Therapeutics.