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Journal of Pharmacology And Experimental Therapeutics, Vol. 29, Issue 1, 533-549, 1926
Copyright © 1926 by American Society for Pharmacology and Experimental Therapeutics

STUDIES OF THE INFRA-RED ABSORPTION SPECTRA OF THE ALKALOIDS I. TROPAN DERIVATIVES

FREDERICK K. BELL 1

1 From the Pharmacological Laboratory of the Johns Hopkins University

1. The infra-red absorption spectra between 1µ and 12µ of tropine, ecgonine, cocaine, tropacocaine, atropine, hyoscyamine, homatropine, noratropine, and scopolamine have been recorded and discussed. These substances may be readily differentiated by their sorption spectra.

2. Of the compounds examined, those containing the hydroxyl group are also readily identified by their absorption spectra.

3. The detection of the presence of the secondary amine group is very difficult, with the experimental method employed, when the hydroxyl group is also present.

4. No characteristic absorption of the tropan nucleus has been found.






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Copyright © 1926 by the American Society for Pharmacology and Experimental Therapeutics.