CONTRIBUTIONS TO THE PHARMACOLOGY OF POSTURE AND OF LABYRINTHINE REFLEXES THE NINETEENTH COMMUNICATION: PYRAMIDON, VERAMON AND VERONAL, WITH SPECIAL REFERENCE TO THE QUANTITATIVE EVALUATION OF STIMULANT AND DEPRESSIVE ACTIONS UPON THE CENTRAL NERVOUS SYSTEM OF MAMMALS

¹ Pharmacological Laboratory of the University of Utrecht (Holland)

It is possible by investigating a great number of postural and labyrinthine reflexes to measure quantitatively the stimulant and depressing action of drugs upon the central nervous system.

As an example are described experiments on rabbits on the action of a combination of veronal and pyramidon (=veramon), which show, that in "veramon" the stimulating action of pyramidon is completely neutralized by veronal, and that on the other hand by pyramidon the depressing action of veronal is, according to the dose given, either strongly delayed, or greatly diminished or completely neutralized.