BLOOD CHEMISTRY IN ACUTE HISTAMINE INTOXICATION

¹ From the Medical Division of the Mayo Clinic, Rochester, Minnesota

In shock-like conditions lasting from three to five hours induced by repeated intravenous injection of histamine, there occurred an increase in the non-protein nitrogen and the urea nitrogen in the blood (fig. 1). There were evidences indicative of impaired renal function and increased protein destruction in the body (fig. 2). There was no consistent change in the chlorides or carbon dioxide combining power of the plasma.

Blood chemistry characteristic of high intestinal obstruction can be partly, but not completely, reproduced by histamine poisoning, at least not by that of a short duration.

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