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Marihuana smoking suppresses luteinizing hormone in women

JH Mendelson, NK Mello, J Ellingboe, AS Skupny, BW Lex and M Griffin

Smoking a single 1-g marihuana cigarette containing 1.8% delta 9- tetrahydrocannabinol induced a 30% suppression of plasma luteinizing hormone levels (P less than .02) in women during the luteal phase of the menstrual cycle. After marihuana placebo cigarette smoking, no luteinizing hormone suppression was observed in the same women under double-blind conditions. Marihuana may have adverse effects upon reproductive function during the luteal phase of the menstrual cycle as a consequence of gonadotropin inhibition.

Volume 237, Issue 3, pp. 862-866, 06/01/1986
Copyright © 1986 by American Society for Pharmacology and Experimental Therapeutics




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Copyright © 1986 by the American Society for Pharmacology and Experimental Therapeutics.