JPET Introducing ALZET?ew Model 2006 Pump

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Ethanol-induced prenatal growth deficiency: changes in fetal body composition

EL Abel and HB Greizerstein

Ethanol (6 g/kg/day) produced intrauterine growth retardation (both body weight and length) in rat fetuses compared to pair-fed controls. Associated with this retardation was an increase in fetal body water and sodium content and a decrease in lipid-free solid content. Comparable electrolyte changes were not observed in maternal blood. These effects in fetal body content are not commonly observed in fetal malnutrition studies and are suggestive of a direct teratogenic effect of ethanol.

Volume 211, Issue 3, pp. 668-671, 12/01/1979
Copyright © 1979 by American Society for Pharmacology and Experimental Therapeutics







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All ASPET Journals Molecular Pharmacology Pharmacological Reviews
 Molecular Interventions Drug Metabolism and Disposition

Copyright © 1979 by the American Society for Pharmacology and Experimental Therapeutics.