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Journal of Pharmacology And Experimental Therapeutics, Vol. 19, Issue 1, 87-95, 1922
Copyright © 1922 by American Society for Pharmacology and Experimental Therapeutics


THE INFLUENCE OF MUSCULAR EXERCISE ON NORMAL CATS COMPARED WITH CATS DEPRIVED OF THE GREATER PART OF THE ADRENALS, WITH SPECIAL REFERENCE TO BODY TEMPERATURE, PULSE AND RESPIRATORY FREQUENCY

G. N. STEWART 1 and J. M. ROGOFF 1

1 From the H. K. Cushing Laboratory of Experimental Medicine, Western Reserve University

Normal cats and cats after removal of the greater portion of the adrenal tissue, or removal of one adrenal and interference with the epinephrin output of the other by section of its nerves, were subjected to prolonged and repeated spells of muscular exercise. No difference which could be attributed to interference with the adrenals was made out in the behavior of the animals as regards resistance to, or recovery from fatigue, or as regards the changes in rectal temperature, pulse or respiratory rate.

After severe muscular exertion a definite, although not a very great depletion of the epinephrin store of an adrenal with its innervation intact, as compared with its previously denervated fellow, may be observed. But even after considerable exertion falling short of great fatigue, no depletion may be present.

Submitted on July 25, 1921







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Copyright © 1922 by the American Society for Pharmacology and Experimental Therapeutics.