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Journal of Pharmacology And Experimental Therapeutics, Vol. 18, Issue 3, 213-220, 1921
Copyright © 1921 by American Society for Pharmacology and Experimental Therapeutics

STUDIES ON THE INFLUENCE OF PHENYLCINCHONINIC ACID AND THE ETHYL ESTER OF PARAMETHYLPHENYLCINCHONINIC ACID ON RENAL EXCRETION

VICTOR C. MYERS 1 and JOHN A. KILLIAN 1

1 From the Laboratory of Pathological Chemistry, New York Post-Graduate Medical School and Hospital, New York

Phenylcinchoninic acid (cinchophen) and the ethyl ester of p-methylphenylcinchoninic acid (tolysin) exercise a general stimulating effect on kidney excretion. This action is most marked in the case of uric acid, but it is possible to demonstrate a similar action in the case of urea and chlorides, provided cases are selected with a slightly high blood concentration of these substance.

Submitted on June 3, 1921




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Copyright © 1921 by the American Society for Pharmacology and Experimental Therapeutics.