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Journal of Pharmacology And Experimental Therapeutics, Vol. 18, Issue 2, 111-119, 1921
Copyright © 1921 by American Society for Pharmacology and Experimental Therapeutics

RESPONSE TO DRUGS OF EXCISED BRONCHI FROM NORMAL AND DISEASED ANIMALS

D. I. MACHT 1 and GIU-CHING TING 1

1 From the Pharmacological Laboratory of the Johns Hopkins University, Baltimore, Maryland

1. Normal preparations of bronchial muscle respond promptly and quickly to the action of certain pharmacological reagents.

2. Bronchial preparations obtained from pathological lungs even in a very fresh condition, respond to the action of the same drugs much less readily or not at all.

3. This difference in the response between normal and pathological bronchial preparations would seem to indicate that in the latter case there is an impairment of the normal physiological properties of bronchial muscle.

Submitted on April 6, 1921






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Copyright © 1921 by the American Society for Pharmacology and Experimental Therapeutics.