![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
1 Department of Neurology, Cornell University Medical College, New York, New York
There is a 24-hr (circadian) cycle of norepinephrine concentration in certain regions of the cat brain and spinal cord, including the cervical cord, pons, region of the substantia nigra-lateral tegmentum, anterior hypothalamus and region of the tuber cinereum, and also of the norepinephrine content of the pineal gland of the cat. A biphasic or ultradian rhythm of norepinephrine concentration is found in the superior colliculus and possibly in the lateral thalamus. Changes in norepinephrine concentration range up to 4-fold. No sex difference in regional norepinephrine concentrations occurs in the cat. The norepinephrine rhythms in different regions of the cat brain, cervical cord and pineal gland are asynchronous, peaking at different times and having different forms. Although the norepinephrine rhythm in the cat pineal gland depends on a rhythm of environmental lighting and is therefore exogenous, the norepinephrine rhythms in the cervical cord and in the anterior hypothalamus persist during 24 hr of light and thus appear to be endogenous. A diurnal cycle of serotonin occurs in the inferior colliculus and in the red nucleus-medial tegmental region between 0700 and 1900 hours, but not in regions in which norepinephrine rhythms are found at the same time. The serotonin rhythm is therefore independent of the norepinephrine rhythm regionally in the cat brain.
Submitted on May 21, 1968
This article has been cited by other articles:
|
|
 |
|
  R. Frederickson, V Burgis, and J. Edwards Hyperalgesia induced by naloxone follows diurnal rhythm in responsivity to painful stimuli Science, November 18, 1977; 198(4318): 756 - 758. [Abstract] [PDF]
|
|
|
|
|
|
D. L. Margules, M. J. Lewis, J. A. Dragovich, and A. S. Margules Hypothalamic Norepinephrine: Circadian Rhythms and the Control of Feeding Behavior Science, November 10, 1972; 178(4061): 640 - 643. [Abstract] [PDF]
|
|
|
|
|
|
J. R. Sladek Jr. Differences in the Distribution of Catecholamine Varicosities in Cat and Rat Reticular Formation Science, October 22, 1971; 174(4007): 410 - 412. [Abstract] [PDF]
|
|
|
|
|
|
I. Hanin, R. Massarelli, and E. Costa Acetylcholine Concentrations in Rat Brain: Diurnal Oscillation Science, October 16, 1970; 170(3955): 341 - 342. [Abstract] [PDF]
|
|
|
|
|
|
J. Ferguson, S. Henriksen, H. Cohen, G. Mitchell, J. Barchas, and W. Dement "Hypersexuality" and Behavioral Changes in Cats Caused by Administration of p-Chlorophenylalanine Science, April 24, 1970; 168(3930): 499 - 501. [Abstract] [PDF]
|
|
|
|
 |
|
 D. J. Reis, D. T. Moorhead II, and N. Merlino Dopa-Induced Excitement in the Cat: Its Relationship to Brain Norepinephrine Concentrations Arch Neurol, January 1, 1970; 22(1): 31 - 39. [Abstract] [PDF]
|
|
 |
 |
 |
|
 |
 |
 |
