JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MARSHALL, E. K.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MARSHALL, E. K., JR.
Journal of Pharmacology And Experimental Therapeutics, Vol. 16, Issue 3, 141-a-154, 1920
Copyright © 1920 by American Society for Pharmacology and Experimental Therapeutics

THE INFLUENCE OF DIURESIS ON THE ELIMINATION OF UREA, CREATININE AND CHLORIDES

E. K. MARSHALL JR. 1

1 From the Pharmacological Laboratories of the Johns Hopkins University and Washington University, School of Medicine

The effect of the ingestion of large quantities of water (water diuresis) on the elimination of creatinine, urea and chloride has been studied in normal men and dogs. The urine volume is frequently increased twenty-fold or more; creatinine is not increased to a measureable extent; urea is increased definitely but never more than two-fold; chlorides are apparently increased but the increase is variable and generally less marked than that of urea. The increases in urea and chloride do not correspond with the maximum increase in water excretion, in fact at the height of the diuresis the chloride elimination generally decreases. During water diuresis the chloride of the plasma may decrease, while the concentrations of urea and creatinine in the plasma do not vary appreciably.

Submitted on July 30, 1920




This article has been cited by other articles:


Home page
 Arch Intern MedHome page
A. P. BRIGGS
THE ACIDOSIS OF NEPHRITIS: ITS CLINICAL SIGNIFICANCE
Arch Intern Med, January 1, 1932; 49(1): 56 - 76.
[Abstract] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1920 by the American Society for Pharmacology and Experimental Therapeutics.