PRESENCE OF TONE IN THE DENERVATED AND IN THE DECENTRALIZED NICTITATING MEMBRANE OF THE SPINAL CAT AND ITS INFLUENCE ON DETERMINATIONS OF SUPERSENSITIVITY

¹ Department of Pharmacology, Harvard Medical School, Boston, Massachusetts

In the article by S. Z. Langer, Vol. 154, No. 1, October 1966, the legend for figure 3 on page 19 should read as follows:

FIG. 3. Magnitude of the tone present at different time intervals after decentralization (DEC) and after denervation (DEN) of the cat's nictitating membrane.

Ordinates, magnitude of the 20-min tone (in percent of the maximal contraction of normal side). Abscissae, time after the operation; note different time scales for A (in hours) and for B (in days). A, first 48 hr after the operation; thin line, schematic representation of the degeneration contraction of the denervated nictitating membrane. The five groups of denervated nictitating membranes correspond to different stages of the degeneration contraction; from left to right groups II, III, IV, V and VII according to Langer and Trendelenburg (1966) (for details, see METHODS). B, 2 to 28 days after the operation. •, denervated nictitating membranes of spinal cats; , denervated nictitating membranes of spinal cats pretreated with reserpine (3 mg/kg i.p., 24 hr before the experiment); , decentralized nictitating membranes of spinal cats; , decentralized nictitating membranes of spinal cats pretreated with reserpine (3 mg/kg i.p., 24 hr prior to experiment); , denervated nictitating membranes of cats under sodium pentobarbital (35 mg/kg i.p.); , denervated nictitating membranes of spinal cats, bilateral adrenalectomy 24 hr prior to the experiment. Shown are means ± S.E. The number of experiments (n) for the groups of untreated spinal cats is shown at the top of the figure. For the remaining groups, means of at least six experiments are shown.