JPET Celsis microsomes equal better data

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rice, A. J.
Right arrow Articles by Long, J. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rice, A. J.
Right arrow Articles by Long, J. P.
Journal of Pharmacology And Experimental Therapeutics, Vol. 154, Issue 3, 539-545, 1966
Copyright © 1966 by American Society for Pharmacology and Experimental Therapeutics

LOCALIZATION OF VENOCONSTRICTOR RESPONSES

A. J. Rice 1, C. R. Leeson 1, and J. P. Long 1

1 Departments of Pharmacology and Anatomy, College of Medicine, University of Iowa, Iowa City, Iowa

The responses of four veins in the dog, the accessory cephalic, lateral saphenous, external iliac and the splenic, to several vasoconstrictor stimuli were observed. The agents used were acetylcholine, norepinephrine and sympathetic nerve stimulation. Only in two veins, the accessory cephalic and lateral saphenous, could vasoconstriction be induced by these treatments. It was observed that the responses were of a localized nature. Nicotine did not produce venoconstriction in any of the preparations. Histologic examination of these regions showed an area that contained valves and was richly invested with smooth muscle. Valves were present also in nonreactive veins; however, these veins lacked any appreciable amount of smooth muscle fibers in the tunica media. It would appear, then, that venoconstriction in these veins involves localized areas containing valves and rich in smooth muscle.

Submitted on April 26, 1966
Accepted on June 23, 1966




This article has been cited by other articles:


Home page
 VASC ENDOVASCULAR SURGHome page
L. B. Schwartz, L. J. Haines, M. F. Massey, W. W. Kerfoot, R. L. McCann, and P.-O. Hagen
Dependence of Rabbit External Jugular Vein Vasoreactivity on Segment Size and Location
Vascular and Endovascular Surgery, January 1, 1994; 28(1): 15 - 21.
[Abstract] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1966 by the American Society for Pharmacology and Experimental Therapeutics.