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Journal of Pharmacology And Experimental Therapeutics, Vol. 15, Issue 5, 475-493, 1920
Copyright © 1920 by American Society for Pharmacology and Experimental Therapeutics

QUANTITATIVE STUDIES IN CHEMOTHERAPY II. THE TRYPANOCIDAL ACTION OF ARSENIC COMPOUNDS

CARL VOEGTLIN 1, HOMER W. SMITH 1, MARIAN M. CRANE 1, KATHERINE D. WRIGHT 1, and MABEL A. CONNELL 1

1 From the Division of Pharmacology, Hygienic Laboratory, United States Public Health Service

1. Differences in the toxicity of various arsenic preparations have been explained on the hypothesis that they must be changed to one type, namely, the trivalent oxides RAs:O, before exerting their principal toxic action.

2. Differences in the trypanocidal activity of these compounds have been explained upon the same hypothesis.

Submitted on May 11, 1920






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Copyright © 1920 by the American Society for Pharmacology and Experimental Therapeutics.