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Journal of Pharmacology And Experimental Therapeutics, Vol. 15, Issue 3, 181-188, 1920
Copyright © 1920 by American Society for Pharmacology and Experimental Therapeutics

THE REACTION OF THE CAT'S UTERUS TO STROPHANTHUS AND CALCIUM

FRED RANSOM 1

1 The Pharmacological Laboratory, London (Royal Free Hospital) School of Medicine for Women, University of London

The movements of the excised cat's uterus, which have been diminished or arrested by placing it in a Ringer's fluid containing no Ca, are restored and usually increased by the addition of strophanthus.

The effect of quite a short exposure of uterine muscle to strophanthus is to make it extraordinarily responsive to Ca.

It is suggested that some forms of post-partum hemorrhage may be due to subsistence upon a diet poor in Ca affecting the efficiency of the uterine muscle and that in such cases strophanthin might be usefully injected intravenously.

Submitted on January 4, 1920






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Copyright © 1920 by the American Society for Pharmacology and Experimental Therapeutics.