JPET

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MACHT, D. I.
Right arrow Articles by ISAACS, S.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MACHT, D. I.
Right arrow Articles by ISAACS, S.
Journal of Pharmacology And Experimental Therapeutics, Vol. 15, Issue 2, 149-165, 1920
Copyright © 1920 by American Society for Pharmacology and Experimental Therapeutics

THE EFFECT OF SOME ANTIPYRETICS ON THE ACUITY OF HEARING

D. I. MACHT 1, J. GREENBERG 1, and S. ISAACS 1

1 From the Pharmacological Laboratory of the Johns Hopkins University

1. The effect of a large number of antipyretic and analgesic drugs and of their combinations was studied in the relation to the acuity of sound perception.

2. It was found that acetanilide, sodium salicylate, acetylsalicylic acid, phenyl salicylate, and some other drugs decrease the threshold of hearing.

3. It was found that acetphenetidin, antipyrine, pyramidon and some other drugs increase the threshold of hearing.

4. The effects of various combinations were found to produce results which in the case of some, were additive, while, in case of other combinations, were of a synergistic character; and the significance of these phenomena is discussed in the text.

Submitted on January 6, 1920




This article has been cited by other articles:


Home page
 Arch Intern MedHome page
M. P. SCHULTZ
THE USE OF AMIDOPYRINE IN RHEUMATIC FEVER
Arch Intern Med, December 1, 1931; 48(6): 1138 - 1155.
[Abstract] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1920 by the American Society for Pharmacology and Experimental Therapeutics.