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Journal of Pharmacology And Experimental Therapeutics, Vol. 148, Issue 2, 270-276, 1965
Copyright © 1965 by American Society for Pharmacology and Experimental Therapeutics

URINARY METABOLITES OF EPINEPHRINE AND NOREPINEPHRINE IN THE CHICKEN

Barbara R. Rennick 1, Marilyn Z. Pryor 1, and Barbara G. Basch 1

1 Department of Physiology, Mount Holyoke College, South Hadley, Massachusetts

The urinary metabolites of epinephrine (EPI) and norepinephrine (NOR) after intravenous injection in the chicken were predominantly 0-methylated in the form of 3-metimoxy-4-hydroxy phenyl glycol and 3-methoxy-4-hydroxy mandelic acid. EPI and NOR administered into the venous renal portal circulation were actively transported in their original form as aminated, free catechols as evidenced by column and paper chromatography.

Accepted on January 12, 1965






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Copyright © 1965 by the American Society for Pharmacology and Experimental Therapeutics.