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Journal of Pharmacology And Experimental Therapeutics, Vol. 145, Issue 3, 315-316, 1964
Copyright © 1964 by American Society for Pharmacology and Experimental Therapeutics

NICOTINE AND RENAL HYPERTENSION IN THE RAT

Duane G. Wenzel 1, Artorntip Wattanapongsiri 1, and Donald Vedral 1

1 Division of Pharmacology, University of Kansas Pharmacy School, Lawrence, Kansas

Chronic treatment of rats with nicotine for 55 weeks first elevated and then depressed the systolic pressure. Pressures of untreated renalhypertensive rats remained elevated, while the concomitant administration of nicotine to renalhypertensive animals reduced systolic pressures below the original level.

Accepted on May 25, 1964






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Copyright © 1964 by the American Society for Pharmacology and Experimental Therapeutics.