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Journal of Pharmacology And Experimental Therapeutics, Vol. 145, Issue 2, 242-246, 1964
Copyright © 1964 by American Society for Pharmacology and Experimental Therapeutics


METABOLIC FATE OF ngr-(3, 4, 5-TRIMETHOXYPHENYL)-ETHYLAMINE (MESCALINE) IN HUMANS: ISOLATION AND IDENTIFICATION OF 3,4, 5-TRIMETHOXYPHENYLACETIC ACID

K. D. Charalampous 1, Antonio Orengo 1, K. E. Walker 1, and John Kinross-Wright 1

1 Department of Psychiatry, Baylor University College of Medicine, and Houston State Psychiatric Institute, Houston, Texas

Human subjects given labeled beta-(3,4 ,5-trimethoxyphyphenyl) -ethylanoine by mouth excrete an average of 81.9% of the administered dose in the urine during the first 12 hours. An average of 26.2% of the administered dose is excreted in the urine as free TMPA. TMPA given to humans by mouth produces no physiological or psychological changes.

Accepted on April 19, 1954







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Copyright © 1964 by the American Society for Pharmacology and Experimental Therapeutics.