JPET

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by James, T. N.
Right arrow Articles by Nadeau, R. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by James, T. N.
Right arrow Articles by Nadeau, R. A.
Journal of Pharmacology And Experimental Therapeutics, Vol. 143, Issue 3, 350-355, 1964
Copyright © 1964 by American Society for Pharmacology and Experimental Therapeutics

THE CHRONOTROPIC AND VAGAL-BLOCKING ACTIONS OF NAPHTHYLISOPROTERENOL STUDIED BY DIRECT PERFUSION OF THE SINUS NODE

Thomas N. James 1 and Reginald A. Nadeau 1

1 Section on Cardiovascular Research, Henry Ford Hospital, Detroit, Michigan

On direct perfusion of the sinus node naphthylisoproterenol has an increasing negative chronotropic effect with increasing concentrations. Concurrent with blocking cardiac acceleration from adrenergic stimuli, naphthylisoproterenol also blocks cardiac inhibition from vagal stimulation.

Submitted on June 28, 1963
Accepted on October 23, 1963






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1964 by the American Society for Pharmacology and Experimental Therapeutics.