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-PHENYLETHYLAMINE IN MAMMALIAN TISSUE AND ITS EFFECT ON MOTOR ACTIVITY IN THE MOUSE
1 The Department of Neuropsychiatry, Osaka University Medical School, Osaka, Japan
The occurrence of
-phenylethylamine in the tissues of rabbits treated with a monoamine oxidase inhibitor has been demonstrated. The tentative identification of the amine was confirmed with material purified from organs of rabbits which had been treated with the injection of both a monoamine oxidase inhibitor and L-phenylalanine.
The concentrations of
-phenylethylamine in various tissues and different regions of the brain of rabbits which had been given monoamine oxidase inhibitors are reported.
The administration of
-phenylethylamine to the mouse resulted in an increased motor activity along with an increased amount of the amine in the brain.