JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hertting, G.
Right arrow Articles by Axelrod, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hertting, G.
Right arrow Articles by Axelrod, J.
Journal of Pharmacology And Experimental Therapeutics, Vol. 136, Issue 3, 289-292, 1962
Copyright © 1962 by American Society for Pharmacology and Experimental Therapeutics

EFFECT OF DECENTRALIZATION AND GANGLIONIC BLOCKING AGENTS ON THE SPONTANEOUS RELEASE OF H3-NOREPINEPHRINE

Georg Hertting 1, Lincoln T. Potter 2, and Julius Axelrod 2

1 Department of Pharmacology, University of Vienna, Vienna, Austria
2 Laboratory of Clinical Science, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland

Decentralization of the superior cervical ganglion slowed the spontaneous release of H3-norepinephrine in the organs innervated by this nerve (submaxillary and parotid glands, striated and smooth eye muscles and iris).

Long-lasting ganglionic blocking agents inhibited the spontaneous release of H3-norepinephrine from rat heart. Chlorisondamine (a long-acting ganglionic blocking agent) elevated the endogenous catecholamine content in rat heart without inhibiting monoamine oxidase.

Submitted on December 27, 1961




This article has been cited by other articles:


Home page
 ScienceHome page
J. Young and L Landsberg
Suppression of sympathetic nervous system during fasting
Science, June 24, 1977; 196(4297): 1473 - 1475.
[Abstract] [PDF]

Home page
 ScienceHome page
J. Axelrod
Noradrenaline: Fate and Control of Its Biosynthesis
Science, August 13, 1971; 173(3997): 598 - 606.
[PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1962 by the American Society for Pharmacology and Experimental Therapeutics.