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Journal of Pharmacology And Experimental Therapeutics, Vol. 129, Issue 4, 428-432, 1960
Copyright © 1960 by American Society for Pharmacology and Experimental Therapeutics


CYCLOPROPANE-EPINEPHRINE INTERACTION ON THE NICTITATING MEMBRANE OF THE SPINAL CAT

J. S. Gravenstein 1, E. T. Sherman 1, and T. W. Andersen 1

1 Division of Anesthesia, University of Florida College of Medicine, Gainesville, Florida

Cyclopropane has no visible effect on the acutely decentralized nictitating membrane of the atropinized, spinal, adrenalectomized cat. Cyclopropane, however, enhances the effect of a continuous infusion with epinephrine on the nictitating membrane. Higher concentrations of cyclopropane are more effective than lower concentrations. Cyclopropane causes greater contractions with larger dosages of epinephrine than with smaller ones.

Submitted on December 19, 1959







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Copyright © 1960 by the American Society for Pharmacology and Experimental Therapeutics.