JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Creese, R.
Right arrow Articles by Zinn, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Creese, R.
Right arrow Articles by Zinn, D.
Journal of Pharmacology And Experimental Therapeutics, Vol. 124, Issue 1, 47-52, 1958
Copyright © 1958 by American Society for Pharmacology and Experimental Therapeutics

TEMPERATURE AND RESTING POTENTIAL OF DIAPHRAGM MUSCLE IN A CO2-BICARBONATE MEDIUM

R. Creese 1, N. W. Scholes 1, D. B. Taylor 1, and Darrell Zinn 1

1 Department of Pharmacology, University of California Medical Center, Los Angeles

The effect of temperature on the isolated rat diaphragm in a carbon-dioxide-bicarbonate medium has been studied with intracellular electrodes. The electrode was pushed through the whole substance of the tissue and the electrical deflexions were recorded by a pen writer.

Mean potentials showed little change after at least 6 hours.

In this medium there was no change in the mean resting potential between 39° C. and 15° C. Lowering the temperature to 5° C. gave a small and insignificant fall of resting potential.

The effects of temperature on the carbondioxide-bicarbonate system are summarized.

Submitted on June 10, 1958






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1958 by the American Society for Pharmacology and Experimental Therapeutics.