JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by George, R.
Right arrow Articles by Way, E. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by George, R.
Right arrow Articles by Way, E. L.
Journal of Pharmacology And Experimental Therapeutics, Vol. 119, Issue 3, 310-316, 1957
Copyright © 1957 by American Society for Pharmacology and Experimental Therapeutics

THE HYPOTHALAMUS AS AN INTERMEDIARY FOR PITUITARYADRENAL ACTIVATION BY ASPIRIN

Robert George 1 and E. Leong Way 1

1 Department of Pharmacology, Schools of Pharmacy and Medicine, University of California, San Francisco

The effect of aspirin on adrenal ascorbic acid in rats with hypothalamic lesions was studied.

Lesions of the median eminence completely blocked the adrenal ascorbic acid depletion which normally occurs within one hour following the administration of aspirin (150 mgm./kgm.).

Partial lesions of the anterior median eminence, as well as lesions placed anterior and dorsal to the median eminence, did not alter the normal response to aspirin.

Submitted on August 24, 1956






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1957 by the American Society for Pharmacology and Experimental Therapeutics.