JPET Celsis microsomes equal better data

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Journal of Pharmacology And Experimental Therapeutics, Vol. 117, Issue 4, 488-493, 1956
Copyright © 1956 by American Society for Pharmacology and Experimental Therapeutics

OXYTOCIC ACTIVITY OF AMINOACETAMIDES AND PROPIONAMIDES

Harry Rosen 1, Albert Blumenthal 1, Patricia N. Townsend 1, Richard Tislow 1, and Joseph Seifter 1

1 Wyeth Institute for Medical Research, Radnor, Pa.

Of 98 substituted aminoacetamides and 10 propionamides screened for oxytocic activity, three compounds, di-n-propylamino-N , N-di-n-propylacetamide, di-n-butylamino-N , N-diethylacetamide and di-iso-butylamino-N , N-diethyl- acetamide were found to be the most active oxytocics.

Submitted on March 7, 1956






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Copyright © 1956 by the American Society for Pharmacology and Experimental Therapeutics.