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Journal of Pharmacology And Experimental Therapeutics, Vol. 114, Issue 1, 10-13, 1955
Copyright © 1955 by American Society for Pharmacology and Experimental Therapeutics

PHARMACOLOGICAL STUDIES WITH DESERPIDINE, A NEW ALKALOID FROM RAUWOLFIA CANESCENS

Jurg A. Schneider 1, A. J. Plummer 1, A. E. Earl 1, W. E. Barrett 1, R. Rinehart 1, and R. C. Dibble 1

1 Research Department, Ciba Pharmaceutical Products, Inc., Summit, New Jersey

The pharmacologic effects of deserpidine were compared to those of reserpine. No significant differences between the effects of the two alkaloids could be found. This indicates that the methoxy group in ring A of reserpine is not essential for its pharmacologic activity.

Submitted on January 3, 1955






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Copyright © 1955 by the American Society for Pharmacology and Experimental Therapeutics.