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Journal of Pharmacology And Experimental Therapeutics, Vol. 111, Issue 2, 147-151, 1954
Copyright © 1954 by American Society for Pharmacology and Experimental Therapeutics

THE ACTION OF ORNITHOGALUM UMBELLATUM ON THE HEART

Russell A. Waud 1

1 Department of Pharmacology, University of Western Ontario, London, Canada

It has been shown that Ornithogalum umbellatum (Star of Bethlehem), a bulbous plant belonging to the lily family, contains a substance having an action very similar, if not identical with, that of the glycosides of digitalis.

Active extracts were prepared with alcohol, acetone and with water and standardized on frogs and cats. The most active bulbs, when assayed by the cat method, showed a potency 1.84 times that of digitalis leaves.

Submitted on January 25, 1954






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