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Journal of Pharmacology And Experimental Therapeutics, Vol. 111, Issue 2, 142-146, 1954
Copyright © 1954 by American Society for Pharmacology and Experimental Therapeutics

THE IN VIVO LIBERATION OF MORPHINE FROM CODEINE IN MAN

Gilbert J. Mannering 1, Arthur C. Dixon 1, Eugene M. Baker III 1, and Taiichi Asami 1

1 Department of Chemistry, 406th Medical General Laboratory, APO 500, c/o Postmaster, San Francisco, California

Each of three human subjects was fed 130 mgm. of codeine sulfate. Urine was collected for twenty-four hours and examined for the presence of morphine. A crystalline material was isolated and identified as morphine.

Submitted on January 21, 1954




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Copyright © 1954 by the American Society for Pharmacology and Experimental Therapeutics.