CONCERNING THE ACTION OF THE IODIDE, BROMIDE AND NITRATE IONS ON THE RESPIRATORY CENTER

¹ From the Physiological and Pharmacological Laboratories of the Johns Hopkins University

From the experiments above described, it was concluded that the iodide, bromide and nitrate ions exert a stimulating effect upon the respiratory center. In case of the iodides this agrees well with the stimulating effect of the iodide ion noted by Macht on the isolated heart and blood vessels (3); and in case of the nitrate the results agree also very well with the difference between the action of the nitrates and nitrites noted by the same author on the ureter (4). This effect of the various ions studied and more particularly of the iodides and bromides is of considerable interest from the therapeutic point of view inasmuch as iodides and bromides are extensively employed in pathological respiratory conditions.