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Journal of Pharmacology And Experimental Therapeutics, Vol. 106, Issue 3, 286-290, 1952
Copyright © 1952 by American Society for Pharmacology and Experimental Therapeutics

THE DISTRIBUTION AND EXCRETION OF THORIUM SULPHATE

J. K. Scott 1, W. F. Neuman 1, and J. F. Bonner 1

1 Division of Pharmacology and Toxicology, Department of Radiation Biology, School of Medicine and Dentistry, The University of Rochester, Rochester, New York

When a soluble thorium compound was administered intravenously to animals it was removed from the blood slowly and most of the thorium was found in the liver, spleen and bone marrow. Following intramuscular injection thorium remained in the injected muscle and following intratracheal injection it remained in the lung. When the compound was given by gavage it was recovered in the feces and no absorption could be demonstrated by the procedures used.

Submitted on July 7, 1952






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Copyright © 1952 by the American Society for Pharmacology and Experimental Therapeutics.