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Journal of Pharmacology And Experimental Therapeutics, Vol. 106, Issue 1, 55-64, 1952
Copyright © 1952 by American Society for Pharmacology and Experimental Therapeutics

EFFECT OF COCAINE ON CARDIAC AUTOMATICITY IN THE DOG

Henning Ruben 1 and Lucien E. Morris 2

1 Vedbaek, Denmark
2 Division of Anesthesiology, Department of Surgery, College of Medicine, State University of Iowa, Iowa City, Iowa

The effect of the administration of epinephrine after cocaine and of the simultaneous injection of cocaine and epinephrine was studied in both conscious and anesthetized dogs. Cocaine was shown to increase the effect of an epinephrine dose on the heart.

Submitted on April 21, 1952






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Copyright © 1952 by the American Society for Pharmacology and Experimental Therapeutics.