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Journal of Pharmacology And Experimental Therapeutics, Vol. 106, Issue 1, 49-54, 1952
Copyright © 1952 by American Society for Pharmacology and Experimental Therapeutics

LABORATORY AND CLINICAL OBSERVATIONS ON THE EFFECT OF REGITINE (C-7337) ON CARDIAC IRREGULARITIES DURING CYCLOPROPANE ANESTHESIA

Lucien E. Morris 1, Chung Sang Yein 1, Bruno Haid 1, and J. M. White Jr. 1

1 Division of Anesthesiology, Department of Surgery, State University of Iowa College of Medicine, Iowa City, Iowa

Regitine reduces the incidence of cyclopropane-epinephrine induced ventricular tachycardia in the dog.

In the dosage in which Regitine was used as premedication before cyclopropane anesthesia in 23 patients there was no significant reduction in ventricular irregularities as compared with the control group. The incidence of ventricular irregularities did not seem to be significantly altered by injection of Regitine during anesthesia.

Submitted on April 21, 1952






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Copyright © 1952 by the American Society for Pharmacology and Experimental Therapeutics.