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Journal of Pharmacology And Experimental Therapeutics, Vol. 104, Issue 2, 162-167, 1952
Copyright © 1952 by American Society for Pharmacology and Experimental Therapeutics

THE ABSORPTION OF NICOTINE IN TOBACCO SMOKING

L. A. Greenberg 1, David Lester 1, and H. W. Haggard 1

1 Laboratory of Applied Physiology, Yale University, New Haven, Conn.

An improved method for the collection and determination of nicotine in tobacco smoke is described.

The smoke from dry cigarettes and cigars contains from 70 to 90 per cent more nicotine than that from similar products containing 11 per cent of water.

In smoking cigarettes or cigars only a small portion of the nicotine content of the smoke is retained in the body with non-inhalation; with inhalation virtually all of the nicotine is absorbed.

Since inhaling is very common among cigarette smokers and rare among cigar smokers, it is likely that the former absorb considerably more nicotine than the latter.

Submitted on October 4, 1951






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