JPET xPharm- The Comprehensive Pharmacology Reference

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Handley, C. A.
Right arrow Articles by Costa, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Handley, C. A.
Right arrow Articles by Costa, P.
Journal of Pharmacology And Experimental Therapeutics, Vol. 101, Issue 3, 283-286, 1951
Copyright © 1951 by American Society for Pharmacology and Experimental Therapeutics

THE RENAL RESPONSE TO THYROXIN ADMINISTRATION

Carroll A. Handley 1, John H. Moyer 1, Orinda Kennedy 1, and Patsy Costa 1

1 Department of Pharmacology, Baylor University College of Medicine, Houston 5, Texas

The daily intravenous administration of thyroxin to dogs causes a marked increase in the glomerular filtration rate, renal plasma flow, tubular transport of dextrose and p-aminohippurate and an increase in renal oxygen consumption. All these changes are proportional and appear to be best explained by assuming that thyroxin increases the number of functional nephrons in the kidney and not to a direct effect on enzyme systems of the renal tubules. Such a concept is in accord with the diuretic action of thyroxin.

Submitted on November 13, 1950






Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
All ASPET Journals Molecular Pharmacology Pharmacological Reviews
Molecular Interventions Drug Metabolism and Disposition

Copyright © 1951 by the American Society for Pharmacology and Experimental Therapeutics.