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Journal of Pharmacology And Experimental Therapeutics, Vol. 101, Issue 1, 63-67, 1951
Copyright © 1951 by American Society for Pharmacology and Experimental Therapeutics

THE ACTION OF SEVERAL PRINCIPLES ANID EXTRACTS OF THE DIGITALIS GROUP ON ISCHEMIC SKELETAL MUSCLE

E. G. Pardo 1, D. Garcia-Tellez 1, and E. C. del Pozo 1

1 Laboratorios Centrales de Investigación de la Industria Nacional Químico-Farmacéutica, and Instituto de Salubridad y Enfermedades Tropicaics, Mexico, D. F.

Experiments were carried out to study whether or not ischemic skeletal muscle, which had been shown to be sensitive to k-strophanthoside, would respond to other cardioactive bodies.

Each of ten drugs tested produced a marked increase in the amplitude of contraction of isehemic skeletal muscle. Possible quantitative differences among several of the preparations are suggested.

Submitted on September 6, 1950




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