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Journal of Pharmacology And Experimental Therapeutics, Vol. 100, Issue 2, 136-140, 1950
Copyright © 1950 by American Society for Pharmacology and Experimental Therapeutics

LOCAL ANTIHISTAMINIC ACTION

James P. Hensen 1

1 Department of Pharmacology, Medical College of Georgia, Augusta

A study of the effects of four locally applied antihistaminic agents against the response to intracutaneous histamine was carried out in rabbits using the trypan blue method.

Pyribenzamine, Decapryn and Neo-Antergan were found to be effective in diminishing the amount of dye infiltration caused by histamine.

Thephorin was found to be completely ineffective in this regard.

Submitted on May 24, 1950






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Copyright © 1950 by the American Society for Pharmacology and Experimental Therapeutics.