JPET Celsis microsomes equal better data

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Journal of Pharmacology And Experimental Therapeutics, Vol. 100, Issue 1, 38-44, 1950
Copyright © 1950 by American Society for Pharmacology and Experimental Therapeutics

COCHLEAR SIGNS OF STREPTOMYCIN INTOXICATION

Joseph E. Hawkins Jr. 1

1 Merck Institute for Therapeutic Research, Rahway, N. J.

A toxic action of streptomycin on the auditory system occurs in the periphery at the end organ, reducing primarily the aural microphonic response. The effect differs from that of quinine, of anoxia and of exposure to loud sounds, which depress the response of the auditory nerve fibres before they affect the microphonic.

Submitted on May 4, 1950




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Copyright © 1950 by the American Society for Pharmacology and Experimental Therapeutics.